The present investigation was aimed to study the antidiabetic and antihyperlipidemic potential of abelmoschus esculentus peel and seed powder aepp and aesp in streptozotocin stzinduced diabetic rats. Evaluation of hepatoprotective activity of abelmoschus moschatus seed in paracetamol induced 44 animals. Abelmoschus esculentus as remedy to manage diabetes. Myricetin as the active principle of abelmoschus moschatus to lower. The hypoglycemic activity of this plants extract was tested by using. Doses which have antidiabetic activity were reported as 50 and 100 mgkg body weight. Pdf antidiabetic activity of abelmoschus esculentus ex. Ethnomedicinal, phytochemical and pharmacological profile of. Petroleum ether and ethyl acetate fractions of the leaves of coccinia cordifolia have potential antidiabetic activity 6061. The hypoglycemic effect of the extract was tested in normal, glucose loading and alloxaninduced diabetic rats. Antidiabetic activity studies of white tea camellia.
Antidiabetic phytoconstituents and their mode of action on. List of all chemicals abelmoschus moschatus malvaceae. Malvaceae is described in medicine for the treatment of diabetes mellitus. This species is regarded as a weed outside its natural habitats. The monech seeds of abelmoschus esculentus having potential in the development of a drug for diabetes due to their antidiabetic activity. Evaluation of antidiabetic activity of euphorbia hirta linn. Antiurolithiatic activity of abelmoschus moschatus seed extracts against zinc disc implantationinduced urolithiasis in rats. The methanolic whole plant extract at high dose 500 mgkg exhibited significant antihyperglycemic activity than whole plant extract at low dose 300 mgkg in diabetic rats.
Antidiabetic activity of alcohol of celosia argentea linn. The present investigation aimed to study the effect of two culinary treatments boiling and roasting on the antidiabetic potential of abelmoschus esculentus fruits and seeds in type 2 diabetic rats. The aromatic seeds of this plant are aphrodisiac, ophthalmic, cardio tonic, antispasmodic and used in the treatment of intestinal complaints and check queasiness. Vyawahare 3 1centre for research and development, prist university, thanjavur, india. Myricelin is the primary active constituents of this plant, which improves insulin sensitivity through increased post receptor insulin signaling mediated by enhancements in irs1associated pi3kinase and glut 4 activity in muscles of obese. The present study was carried out to evaluate the antidiabetic activity of vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days. The hypoglycemic activity of myricetin has been investigated in streptozotocininduced diabetic rats 94 using an i. Abelmoschus moschatus is an aromatic and medicinal plant that has been widely introduced across tropical, subtropical and temperate regions of the world. Panax, cinnamomum verum, abelmoschus moschatus, vachellia nilotica, achyranthes, fabaceae. Animal models to test drugs with potential antidiabetic activity t. The outcomes of lipid profile confirmed the potent antidiabetic activity of bark and root of o. Antidiabetic activity of aqueous and methanol extract and fractions of gongronema latifolium leaves in alloxan diabetic rats p. M department of veterinary physiology and biochemistry, faculty of veterinary medicine, university of abuja, pmb 117, abuja, nigeria. Antiurolithiatic activity of abelmoschus moschatus seed extracts.
Preeti sen, kamlesh sahu, pushpa prasad, shashikant chandrakar, ram kumar sahu, amit roy. The effect of boiling and roasting on the antidiabetic activity of abelmoschus esculentus okra fruits and seeds in type 2 diabetic rats was. Antidiabetic activity of the aqueous extracts of foeniculum vulgare on streptozotocininduced diabetic rats t anitha1, 2c balakumar,k b ilango 3, c benedict jose,d vetrivel3. Abelmoschus moschatus, urolithiasis, zinc disc implantation. P abelmoschus moschatus malvaceae chemical part all parts. Myricetin as the active principle of abelmoschus moschatus to lower plasma glucose in. Evaluation of antidiabetic activity of isolated compound.
Approach to phytochemistry and mechaniasm of action of plants having antidiabetic activity. Complementary and alternative medicine for type 2 diabetes. Antidiabetic activity of abelmoschus esculentus ex maradi okra fruit in alloxaninduced diabetic rats article pdf available march 2018 with 1,529 reads how we measure reads. Ethnomedicinal, phytochemical and pharmacological profile of genus abelmoschus onakpa m. Abelmoschus esculentus linn, antidiabetic activity, oral glucose tolerance test, aqueous and ethanolic extracts, insulin, introduction diabetes mellitus is a metabolic disorder characterized by hyperglycemia and alterations in carbohydrate, fat and protein metabolism, associated with absolute or. Comparison with the antiviral activity of propolis.
Abelmoschus esculentus are having potential in the. Antidiabetic activity of the compounds isolated from rhus mysorensis plant extract doi. Myricetin an isolated compound from abelmoschus moschatus showed ic 50 of 0. Punica granatum, satureja khuzestanica and bauhinia forficate. A rewiew on antidiabetic angiospermic plants from the. The musk mallow abelmoschus moschatus improves insulin resistance. Aromatic and medicinal plants with antidiabetic potential. Enzymes inhibitors from natural sources with antidiabetic. Abelmoschus esculentus, okra, diabetes mellitus, diabetic nephropathy. Chaenomeles sinensis is belongs to family rosaceae. Crude fiber, total phenolic content, and in vitro free radical scavenging capacity of the various culinary forms of the fruits and seeds were assessed. Jcprc5 269 protective effect of methanolic extract of abelmoschus moschatus seeds against calcium oxalate urolithiasis in rats a. Evaluation of antidiabetic activity of euphorbia hirta. The results from this study showed that the antioxidant activities of a.
Diabetes mellitus is a complex metabolic disorder that affects between 6 to 20% of the population in western industrialized societies, with an estimated worldwide prevalence of 150 million people in 2000, a number that is expected to increase to 220. It has repeatedly escaped from cultivation to become naturalized, primarily in cultivated, ruderal and seminatural areas. Abelmoschus esculentus okra international journal of herbal. Abelmoschus moschatus, alangium salvifolium, azadirachta indica, bidens pilosa, boerhaavia diffusa, capsicum frutescens. Hence, it was concluded that gossypin has potent antidiabetic activity in streptozotocininduced experimental diabetes in rats. Shamim hossain, naim hassan, biplab kumar dash, md. Antidiabetic activity of medicinal plants and its relationship with their antioxidant property. Evaluation of in vitro anti diabetic activity of selected plant extracts sindhu. This effort is seen towards providing the evidence support to motivate more scientific research to uncover more scientific nutritional properties of abelmoschus esculentus that may be benefited by the modern medicine, thus suggesting new potential target for drug discovery. Antidiabetic potential of purple okra abelmoschus esculentus l. Effect of boiling and roasting on the antidiabetic. These results revealed that methanolic extracts of abelmoschus esculentus have better antioxidant and antidiabetic activity than ethanol and aqueous extracts which support the medicinal properties. Type 2 dm, which accounts for over 90% of the cases, is associated with disordered.
Nutritional quality and health benefits of okra abelmoschus esculentus. Evaluation of antidiabetic activity of abelmoschus esculentus extracts body weight and blood glucose levels of rats were studied to determine the effectiveness of abelmoschus esculentus extracts. Diabetes epidemiology as a tool to trigger diabetic research and care. The following medicinal plants products or extracts showed promising effects as enzyme inhibitors. Antiurolithiatic activity of abelmoschus moschatus seed. The aim was to evaluate the antiurolithiatic activity of abelmoschus moschatus seed extracts in rats. In vitro antidiabetic activity of cardiospermum halicacabum leaves extracts by stalin. Antidiabetic activity of the compounds isolated from. The main objective of this work is to evaluate the in vitro anti diabetic activity of methanolic. Okolo rural dwellers in nigeria often resort to herbal remedy and dietary control in the treatment of diabetes mellitus dm. Research article open access evaluation of abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays mir z gul1, lepakshi m bhakshu1, farhan ahmad2, anand k kondapi2, insaf a qureshi2 and irfan a ghazi1 abstract. Emblica officinalis, their combination triphala for their antidiabetic activity and their relation with. Original article experimental evaluation of antidiabetic. Antidiabetic activity of vinca rosea extracts in alloxan.
The ethanolic extracts and the hexane and chloroform fractions of leaves and fruit peels showed promising antidiabetic activity in stzs model. Antidiabetic activity of abelmoschus esculentus fruit extract. There was a sudden increase in body weight on 28th day of the study with the. Home pharmacogn j, vol 10, issue 1, janfeb, 2018 antidiabetic activity studies of white tea camellia sinensis l. The obtained data were comparable with gliclazide, a standard reference drug for diabetes. Candida albicans were used to evaluate its antimicrobial activity. It improves insulin sensitivity through increased postreceptor insulin signaling mediated by enhancements in irs1associated pi3kinase and glut 4 activity in muscles of obese zucker rats 23. Antiurolithiatic activity of abelmoschus moschatus seed extracts against zinc disc implantationinduced urolithiasis in rats abstract background. Acute toxicity of aepp and aesp was studied in rats at 2000 mgkg dose and diabetes was induced in rats by administration of stz 60 mgkg, i. Serum glucose levels and activities of enzymes viz.
Ashrafuzzaman sapon, monokesh kumer sen abstract in the last few years, there has been an exponential growth in the field of herbal medicine and gaining. Forty male albino rats were divided into four groups. Improvement of insulin sensitivity in obese zucker rats by myricetin extracted from abelmoschus moschatus. The leaves of bauhinia purpurea orchid tree were found to possess, in addition to antidiabetic activity, antioxidant and antihyperlipidemic activities 24. A rewiew on antidiabetic angiospermic plants from the regions of uttarakhand, india 16 s r. The hypoglycemic activity of myricetin isolated from. Evaluation of in vitro anti diabetic activity of selected. The potent antidiabetic effect of the plant extract suggests the presence of potent antidiabetic active principles, which produced antihyperglycemic effect in diabetic rats 15,19. Department of medicinal chemistry and pharmacognosy, college of pharmacy, university of illinois at.
Abelmoschus moschatus is an aromatic medicinal plant commonly found in bangladesh and nearly india. Myricetin is a phenolic compound isolated from the aerial part of abelmoschus moschatus malvaceae. Evaluation of hepatoprotective activity of abelmoschus. This study was conducted to compare the ameliorative effect of nigella sativa and propolis methanol extract on streptozotocininduced diabetic male rats and treating diabetic nephropathy. The antidiabetic activity of nigella sativa and propolis. On administration of graded doses of berberine to normal and. The present study was designed to investigate the glucose uptake of antidiabetic activity crude nhexane,ethanol, methanol and aqueous leaf.
Though different types of oral hypoglycemic agents are available along with insulin for the treatment of diabetes mellitus. Abelmoschus moschatus medik malvaceae whole plant contains myricelin which enhances insulin sensitivity through increasing postreceptor transduction in muscle. The commonly used techniques for removing renal calculi are associated with the risk of acute renal injury and increase in stone recurrence which indicates an urgent need for alternate therapy. Bidens pilosa referred as black jack is a perennial flowering plant belonging to family asteraceae. The mechanism of action of myricetin seems to be the. Abelmoschus is a genus of about fifteen species of flowering plants in.
The aim was to evaluate the antiurolithiatic activity of abelmoschus. Pdf evaluation of abelmoschus moschatus extracts for antioxidant. Artemis sphaerocephala krasch 12 antioxidant effect of artemis sphaerocephala a. Woldegiorgis abstract okra abelmoschus esculentus is an economically important vegetable crop grown in tropical and subtropical parts of the world. Shows comparison of mean blood glucose levels between normal control, diabetic control, standard and test groups in aqueous extract treated rats. Research article open access evaluation of abelmoschus. Ethnomedicinal, phytochemical and pharmacological profile. Antioxidant and antidiabetic properties of abelmoschus.
Kuntze ethanolic extracts in streptozotocinnicotinamide induced diabetic rats. The most useful medicinal herbs to treat diabetes biomedical. Approach to phytochemistry and mechaniasm of action of. Myricetin might be used as a model substance for the development of antidiabetic compounds 5. Hypoglycemic activity due to increase in the peripheral metabolism of glucose was seen in some plants and these experiments were carried out on rabbits with experimentally induced diabetes 23. Nair1, vaibhavi kavrekar1, anshu mishra1 1 department of biotechnology, mount carmel college, bangalore, karnataka, india abstract.
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